Okadaic Acid ELISA
Cat. No.: 5191OKA
Okadaic acid (OA) and its analogues, the dinophysis toxins (DTX-1, DTX-2, and DTX-3), together form the group of OA-toxins. These toxins are lipophilic and heat stable, are produced by dinoflagellates, namely the benthic dinoflagellate Prorocentrum and the planktonic forms of Dinophysis.
OA-group toxins can be found in various species of shellfish and cause Diarrheic Shellfish Poisoning (DSP), which is characterized by symptoms such as diarrhea, nausea, vomiting and abdominal pain.
OA is a specific inhibitor of eukaryotic phosphatases which remove phosphate from serine and threonine residues. It’s also identified as a tumor promoter in rodents and smooth muscle stimulant.
The okadaic acid ELISA is used for the quantitative analysis of okadaic acid in shellfish samples (mussel, scallop, oyster). The calibration curve is virtually linear in the range 0.2 to 10 ng/ml.
The kit uses a polyclonal rabbit antibody which shows the following cross-reactivities: okadaic acid (100%), dinophysis toxins DTX-1 (78%), dinophysis toxins DTX-2 (2.6%), saxitoxin (0%), and domoic acid (0%).
Detailed information of this ELISA is given in the Product Information Sheet.
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